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Cellosaurus UD-SCC-3 (CVCL_E326)

[Text version]
Cell line name UD-SCC-3
Synonyms UD-SCC 3; UD-SCC3; University of Dusseldorf-Squamous Cell Carcinoma-3
Accession CVCL_E326
Resource Identification Initiative To cite this cell line use: UD-SCC-3 (RRID:CVCL_E326)
Comments Doubling time: 31 hours (PubMed=10628319; PubMed=18487078).
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu224Ter (c.670G>T); Zygosity=Unspecified (PubMed=10628319).
Disease Laryngeal squamous cell carcinoma (NCIt: C4044)
Squamous cell carcinoma of the larynx (ORDO: Orphanet_494550)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 45Y
Category Cancer cell line
Publications

PubMed=10628319
Ballo H., Koldovsky P., Hoffmann T.K., Balz V., Hildebrandt B., Gerharz C.-D., Bier H.
Establishment and characterization of four cell lines derived from human head and neck squamous cell carcinomas for an autologous tumor-fibroblast in vitro model.
Anticancer Res. 19:3827-3836(1999)

PubMed=15495191; DOI=10.1002/gcc.20119
Raschke S., Balz V., Efferth T., Schulz W.A., Florl A.R.
Homozygous deletions of CDKN2A caused by alternative mechanisms in various human cancer cell lines.
Genes Chromosomes Cancer 42:58-67(2005)

PubMed=16331601; DOI=10.1002/ijc.21514
Muller A., Sonkoly E., Eulert C., Gerber P.A., Kubitza R., Schirlau K., Franken-Kunkel P., Poremba C., Snyderman C.H., Klotz L.-O., Ruzicka T., Bier H., Zlotnik A., Whiteside T.L., Homey B., Hoffmann T.K.
Chemokine receptors in head and neck cancer: association with metastatic spread and regulation during chemotherapy.
Int. J. Cancer 118:2147-2157(2006)

PubMed=18487078; DOI=10.1016/j.oraloncology.2008.02.006
Hoffmann T.K., Sonkoly E., Hauser U., van Lierop A., Whiteside T.L., Klussmann J.P., Hafner D., Schuler P.J., Friebe-Hoffmann U., Scheckenbach K., Erjala K., Grenman R., Schipper J., Bier H., Balz V.
Alterations in the p53 pathway and their association with radio- and chemosensitivity in head and neck squamous cell carcinoma.
Oral Oncol. 44:1100-1109(2008)

Cross-references
Encyclopedic resources Wikidata; Q54990108
Polymorphism and mutation databases Cosmic; 932283
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number13