ID   UD-SCC-3
AC   CVCL_E326
SY   UD-SCC 3; UD-SCC3; University of Dusseldorf-Squamous Cell Carcinoma-3
DR   Cosmic; 932283
DR   Wikidata; Q54990108
RX   PubMed=10628319;
RX   PubMed=15495191;
RX   PubMed=16331601;
RX   PubMed=18487078;
CC   Doubling time: 31 hours (PubMed=10628319; PubMed=18487078).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu224Ter (c.670G>T); Zygosity=Unspecified (PubMed=10628319).
CC   Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
DI   NCIt; C4044; Laryngeal squamous cell carcinoma
DI   ORDO; Orphanet_494550; Squamous cell carcinoma of the larynx
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   45Y
CA   Cancer cell line
DT   Created: 22-10-12; Last updated: 19-12-24; Version: 13
//
RX   PubMed=10628319;
RA   Ballo H., Koldovsky P., Hoffmann T.K., Balz V., Hildebrandt B.,
RA   Gerharz C.-D., Bier H.;
RT   "Establishment and characterization of four cell lines derived from
RT   human head and neck squamous cell carcinomas for an autologous
RT   tumor-fibroblast in vitro model.";
RL   Anticancer Res. 19:3827-3836(1999).
//
RX   PubMed=15495191; DOI=10.1002/gcc.20119;
RA   Raschke S., Balz V., Efferth T., Schulz W.A., Florl A.R.;
RT   "Homozygous deletions of CDKN2A caused by alternative mechanisms in
RT   various human cancer cell lines.";
RL   Genes Chromosomes Cancer 42:58-67(2005).
//
RX   PubMed=16331601; DOI=10.1002/ijc.21514;
RA   Muller A., Sonkoly E., Eulert C., Gerber P.A., Kubitza R.,
RA   Schirlau K., Franken-Kunkel P., Poremba C., Snyderman C.H., Klotz L.-O.,
RA   Ruzicka T., Bier H., Zlotnik A., Whiteside T.L., Homey B.,
RA   Hoffmann T.K.;
RT   "Chemokine receptors in head and neck cancer: association with
RT   metastatic spread and regulation during chemotherapy.";
RL   Int. J. Cancer 118:2147-2157(2006).
//
RX   PubMed=18487078; DOI=10.1016/j.oraloncology.2008.02.006;
RA   Hoffmann T.K., Sonkoly E., Hauser U., van Lierop A., Whiteside T.L.,
RA   Klussmann J.P., Hafner D., Schuler P.J., Friebe-Hoffmann U.,
RA   Scheckenbach K., Erjala K., Grenman R., Schipper J., Bier H.,
RA   Balz V.;
RT   "Alterations in the p53 pathway and their association with radio- and
RT   chemosensitivity in head and neck squamous cell carcinoma.";
RL   Oral Oncol. 44:1100-1109(2008).
//