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Cellosaurus YES-2 (CVCL_E322)

[Text version]
Cell line name YES-2
Synonyms YES 2; YES2
Accession CVCL_E322
Resource Identification Initiative To cite this cell line use: YES-2 (RRID:CVCL_E322)
Comments Population: Japanese.
Doubling time: 22.9 hours (PubMed=1770930); 67.2 hours (DOI=10.5833/jjgs.27.1885); 23.7 hours (Note=At 102th passage) (CelloPub=CLPUB00005).
Omics: Array-based CGH.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Esophagus; UBERON=UBERON_0001043.
HLA typing Source: PubMed=18575732
Class I
HLA-AA*24
HLA-BB*01,40
HLA-CC*03,07
Disease Esophageal squamous cell carcinoma (NCIt: C4024)
Squamous cell carcinoma of the esophagus (ORDO: Orphanet_99977)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_S526 (YES-2CSC)
Sex of cell Male
Age at sampling 81Y
Category Cancer cell line
Publications

PubMed=1770930
Murakami T., Nakamura M., Kusanagi H., Suzuki T.
Establishment and characterization of human esophageal carcinoma cell lines -- especially the role of the serum-free culture.
Nihon Geka Gakkai Zasshi 92:1563-1570(1991)

CLPUB00005
Nakamura M., Murakami T., Sakata K., Kusanagi H., Saeki T., Uchisako H., Hayashi H., Tangoku A., Suzuki T.
Establishment and characterization of a new human esophageal cancer cell line (YES-2).
Bull. Yamaguchi Med. Sch. 41:149-153(1994)

DOI=10.5833/jjgs.27.1885
Kusanagi H.
Effect of epidermal growth factor (EGF) on human esophageal cancer cell lines in a protein-free medium and the expression of EGF receptors on the cells.
Nihon Shokaki Geka Gakkai Zasshi 27:1885-1891(1994)

PubMed=8590302; DOI=10.1089/jir.1995.15.1005
Oka M., Hirose K., Iizuka N., Aoyagi K., Yamamoto K., Abe T., Hazama S., Suzuki T.
Cytokine mRNA expression patterns in human esophageal cancer cell lines.
J. Interferon Cytokine Res. 15:1005-1009(1995)

PubMed=8974001; DOI=10.1089/jir.1996.16.1001
Oka M., Iizuka N., Yamamoto K., Gondo T., Abe T., Hazama S., Akitomi Y., Koishihara Y., Ohsugi Y., Ooba Y., Ishihara T., Suzuki T.
The influence of interleukin-6 on the growth of human esophageal cancer cell lines.
J. Interferon Cytokine Res. 16:1001-1006(1996)

PubMed=11115554; DOI=10.3892/ijo.18.1.157
Fujii T., Kato S., Yamana H., Tanaka Y., Fujita H., Shirouzu K., Morimatsu M.
Expression of G1 cell cycle markers and the effect of adenovirus-mediated overexpression of p21Waf-1 in squamous cell carcinoma of the esophagus.
Int. J. Oncol. 18:157-163(2001)

PubMed=18575732; DOI=10.3892/or.20.1.155
Kawaoka T., Oka M., Takashima M., Ueno T., Yamamoto K., Yahara N., Yoshino S., Hazama S.
Adoptive immunotherapy for pancreatic cancer: cytotoxic T lymphocytes stimulated by the MUC1-expressing human pancreatic cancer cell line YPK-1.
Oncol. Rep. 20:155-163(2008)

PubMed=18973137; DOI=10.1002/gcc.20626
Sugimoto T., Seki N., Shimizu S., Kikkawa N., Tsukada J., Shimada H., Sasaki K., Hanazawa T., Okamoto Y., Hata A.
The galanin signaling cascade is a candidate pathway regulating oncogenesis in human squamous cell carcinoma.
Genes Chromosomes Cancer 48:132-142(2009)

PubMed=20515944; DOI=10.1158/1535-7163.MCT-09-0918; PMCID=PMC2884061
Seki N., Toh U., Sayers T.J., Fujii T., Miyagi M., Akagi Y., Kusukawa J., Kage M., Shirouzu K., Yamana H.
Bortezomib sensitizes human esophageal squamous cell carcinoma cells to TRAIL-mediated apoptosis via activation of both extrinsic and intrinsic apoptosis pathways.
Mol. Cancer Ther. 9:1842-1851(2010)

PubMed=21191746; DOI=10.1007/s11684-010-0260-x
Ji J.-F., Wu K., Wu M., Zhan Q.-M.
p53 functional activation is independent of its genotype in five esophageal squamous cell carcinoma cell lines.
Front. Med. China 4:412-418(2010)

Cross-references
Cell line databases/resources cancercelllines; CVCL_E322
Encyclopedic resources Wikidata; Q54995400
Gene expression databases GEO; GSM301575
Polymorphism and mutation databases Cosmic; 2395009
Progenetix; CVCL_E322
Entry history
Entry creation22-Oct-2012
Last entry update05-Oct-2023
Version number16