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Cellosaurus EC9706 (CVCL_E307)

[Text version]
Cell line name EC9706
Synonyms Ec9706; EC-9706
Accession CVCL_E307
Resource Identification Initiative To cite this cell line use: EC9706 (RRID:CVCL_E307)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=28807831). Originally thought to originate from a 65 year old male patient with a esophagal squamous cell carcinoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00633.
Population: African American.
Doubling time: 26 hours (PubMed=12476413).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Children:
CVCL_5V05 (EC9706 clone EC1)CVCL_5V06 (EC9706 clone EC2)CVCL_5V07 (EC9706 clone EC3)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
STR profile Source(s): PubMed=28851942

Markers:
AmelogeninX
CSF1PO9,10
D2S133817
D3S135818
D5S81811,12
D7S8208,12
D8S117912,13
D13S31712,13.3
D16S5399,10
D18S5116
D19S43313,14
D21S1127,28
FGA21
TH017
TPOX8,12
vWA16,18

Run an STR similarity search on this cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=12476413
Han Y.-L., Wei F., Xu X., Cai Y., Chen B.-S., Wang J., Xia S.-H., Hu H., Huang X.-P., Han Y.-S., Wu M., Wang M.-R.
Establishment and comparative genomic hybridization analysis of human esophageal carcinomas cell line EC9706.
Zhonghua Yi Xue Yi Chuan Xue Za Zhi 19:455-457(2002)

PubMed=21191746; DOI=10.1007/s11684-010-0260-x
Ji J.-F., Wu K., Wu M., Zhan Q.-M.
p53 functional activation is independent of its genotype in five esophageal squamous cell carcinoma cell lines.
Front. Med. China 4:412-418(2010)

PubMed=28807831; DOI=10.1016/j.jhep.2017.08.002
Rebouissou S., Zucman-Rossi J., Moreau R., Qiu Z.-X., Hui L.-J.
Note of caution: contaminations of hepatocellular cell lines.
J. Hepatol. 67:896-897(2017)

PubMed=28851942; DOI=10.1038/s41598-017-09660-w; PMCID=PMC5575032
Bian X.-C., Yang Z.-L., Feng H.-L., Sun H., Liu Y.-Q.
A combination of species identification and STR profiling identifies cross-contaminated cells from 482 human tumor cell lines.
Sci. Rep. 7:9774-9774(2017)

Cross-references
Cell line databases/resources TOKU-E; 3567
Anatomy/cell type resources BTO; BTO:0005757
Chemistry resources ChEMBL-Cells; CHEMBL4295473
ChEMBL-Targets; CHEMBL4296412
PubChem_Cell_line; CVCL_E307
Encyclopedic resources Wikidata; Q54831915
Experimental variables resources EFO; EFO_0022576
Entry history
Entry creation22-Oct-2012
Last entry update10-Sep-2024
Version number17