ID   EC9706
AC   CVCL_E307
SY   Ec9706; EC-9706
DR   BTO; BTO:0005757
DR   ChEMBL-Cells; CHEMBL4295473
DR   ChEMBL-Targets; CHEMBL4296412
DR   PubChem_Cell_line; CVCL_E307
DR   TOKU-E; 3567
DR   Wikidata; Q54831915
RX   PubMed=12476413;
RX   PubMed=21191746;
RX   PubMed=28851942;
CC   Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=28807831). Originally thought to originate from a 65 year old male patient with a esophagal squamous cell carcinoma.
CC   Population: African American.
CC   Doubling time: 26 hours (PubMed=12476413).
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
ST   Source(s): PubMed=28851942
ST   Amelogenin: X
ST   CSF1PO: 9,10
ST   D13S317: 12,13.3
ST   D16S539: 9,10
ST   D18S51: 16
ST   D19S433: 13,14
ST   D21S11: 27,28
ST   D2S1338: 17
ST   D3S1358: 18
ST   D5S818: 11,12
ST   D7S820: 8,12
ST   D8S1179: 12,13
ST   FGA: 21
ST   TH01: 7
ST   TPOX: 8,12
ST   vWA: 16,18
DI   NCIt; C27677; Human papillomavirus-related cervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0030 ! HeLa
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 22-10-12; Last updated: 30-01-24; Version: 15
//
RX   PubMed=12476413;
RA   Han Y.-L., Wei F., Xu X., Cai Y., Chen B.-S., Wang J., Xia S.-H.,
RA   Hu H., Huang X.-P., Han Y.-S., Wu M., Wang M.-R.;
RT   "Establishment and comparative genomic hybridization analysis of human
RT   esophageal carcinomas cell line EC9706.";
RL   Zhonghua Yi Xue Yi Chuan Xue Za Zhi 19:455-457(2002).
//
RX   PubMed=21191746; DOI=10.1007/s11684-010-0260-x;
RA   Ji J.-F., Wu K., Wu M., Zhan Q.-M.;
RT   "p53 functional activation is independent of its genotype in five
RT   esophageal squamous cell carcinoma cell lines.";
RL   Front. Med. China 4:412-418(2010).
//
RX   PubMed=28851942; DOI=10.1038/s41598-017-09660-w;
RA   Bian X.-C., Yang Z.-L., Feng H.-L., Sun H., Liu Y.-Q.;
RT   "A combination of species identification and STR profiling identifies
RT   cross-contaminated cells from 482 human tumor cell lines.";
RL   Sci. Rep. 7:9774-9774(2017).
//