Cellosaurus cell line RSAR001 (CVCL

Cellosaurus RSAR001 (CVCL_E2TL)

[Text version]

Cell line name

RSAR001

Synonyms

RSAR1; F_PDO_000001

Accession

CVCL_E2TL

Resource Identification Initiative

To cite this cell line use: RSAR001 (RRID:CVCL_E2TL)

Comments

Part of: Fukushima Translational Research Project Patient-Derived Organoids (F-PDO) collection.
Population: Japanese.
Doubling time: ~35 hours (PubMed=30194147).
Omics: Deep exome analysis.
Omics: Transcriptome analysis by RNAseq.
Caution: While established by the F-PDO project, this is a cell line and not an organoid.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.

Sequence variations

Gene fusion; HGNC; HGNC:783; ATF1 + HGNC; HGNC:3508; EWSR1; Name(s)=EWSR1-ATF1, EWS-ATF; Note=Type 1: EWSR1 exon 8 fused to ATF1 exon 4 (PubMed=30194147).

Disease

Clear cell sarcoma of soft tissue (NCIt: C3745)
Soft tissue sarcoma (ORDO: Orphanet_3394)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

43Y

Category

Cancer cell line

STR profile

Source(s): PubMed=36959380

Markers:

Amelogenin	X,Y
CSF1PO	13
D3S1358	15
D5S818	10,12
D7S820	10,12
D8S1179	10,15
D13S317	12,13
D16S539	10
D18S51	15
D21S11	29
FGA	22
Penta D	10
Penta E	14
TH01	6,9
TPOX	9
vWA	17

Web pages

https://www.fmu.ac.jp/home/trc/en/contract-research-provision/f-pdo/

Publications

PubMed=30194147; DOI=10.21873/anticanres.12822
Hakozaki M., Tamura H., Dobashi Y., Yoshida A., Kato K., Tajino T., Yamada H., Kaneuchi Y., Katahira K., Ezaki J., Waguri S., Konno S., Watanabe S.
Establishment and characterization of a novel human clear-cell sarcoma of soft-tissue cell line, RSAR001, derived from pleural effusion of a patient with pleural dissemination.
Anticancer Res. 38:5035-5042(2018)

PubMed=36959380; DOI=10.1038/s41416-023-02222-0; PMCID=PMC10147623
Rasmussen S.V., Wozniak A., Lathara M., Goldenberg J.M., Samudio B.M., Bickford L.R., Nagamori K., Wright H., Woods A.D., Chauhan S., Lee C.-J., Rudzinski E.R., Swift M.K., Kondo T., Fisher D.E., Imyanitov E.N., Machado I., Llombart-Bosch A., Andrulis I.L., Gokgoz N., Wunder J.S., Moritake H., Nakamura T., Srinivasa G., Thway K., Jones R.L., Huang P.H., Berlow N.E., Schoffski P., Keller C.
Functional genomics of human clear cell sarcoma: genomic, transcriptomic and chemical biology landscape for clear cell sarcoma.
Br. J. Cancer 128:1941-1954(2023)

Cross-references

Cell line collections (Providers)

CancerTools; 160990

Sequence databases

EGA; EGAD00001008611

Entry history

Entry creation

10-Sep-2024

Last entry update

19-Dec-2024

Version number