ID   RSAR001
AC   CVCL_E2TL
SY   RSAR1; F_PDO_000001
DR   CancerTools; 160990
DR   EGA; EGAD00001008611
RX   PubMed=30194147;
RX   PubMed=36959380;
WW   https://www.fmu.ac.jp/home/trc/en/contract-research-provision/f-pdo/
CC   Part of: Fukushima Translational Research Project Patient-Derived Organoids (F-PDO) collection.
CC   Population: Japanese.
CC   Doubling time: ~35 hours (PubMed=30194147).
CC   Sequence variation: Gene fusion; HGNC; HGNC:783; ATF1 + HGNC; HGNC:3508; EWSR1; Name(s)=EWSR1-ATF1, EWS-ATF; Note=Type 1: EWSR1 exon 8 fused to ATF1 exon 4 (PubMed=30194147).
CC   Omics: Deep exome analysis.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Caution: While established by the F-PDO project, this is a cell line and not an organoid.
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
ST   Source(s): PubMed=36959380
ST   Amelogenin: X,Y
ST   CSF1PO: 13
ST   D13S317: 12,13
ST   D16S539: 10
ST   D18S51: 15
ST   D21S11: 29
ST   D3S1358: 15
ST   D5S818: 10,12
ST   D7S820: 10,12
ST   D8S1179: 10,15
ST   FGA: 22
ST   Penta D: 10
ST   Penta E: 14
ST   TH01: 6,9
ST   TPOX: 9
ST   vWA: 17
DI   NCIt; C3745; Clear cell sarcoma of soft tissue
DI   ORDO; Orphanet_3394; Soft tissue sarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   43Y
CA   Cancer cell line
DT   Created: 10-09-24; Last updated: 19-12-24; Version: 2
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RX   PubMed=30194147; DOI=10.21873/anticanres.12822;
RA   Hakozaki M., Tamura H., Dobashi Y., Yoshida A., Kato K., Tajino T.,
RA   Yamada H., Kaneuchi Y., Katahira K., Ezaki J., Waguri S., Konno S.,
RA   Watanabe S.;
RT   "Establishment and characterization of a novel human clear-cell
RT   sarcoma of soft-tissue cell line, RSAR001, derived from pleural
RT   effusion of a patient with pleural dissemination.";
RL   Anticancer Res. 38:5035-5042(2018).
//
RX   PubMed=36959380; DOI=10.1038/s41416-023-02222-0; PMCID=PMC10147623;
RA   Rasmussen S.V., Wozniak A., Lathara M., Goldenberg J.M., Samudio B.M.,
RA   Bickford L.R., Nagamori K., Wright H., Woods A.D., Chauhan S., Lee C.-J.,
RA   Rudzinski E.R., Swift M.K., Kondo T., Fisher D.E., Imyanitov E.N.,
RA   Machado I., Llombart-Bosch A., Andrulis I.L., Gokgoz N., Wunder J.S.,
RA   Moritake H., Nakamura T., Srinivasa G., Thway K., Jones R.L., Huang P.H.,
RA   Berlow N.E., Schoffski P., Keller C.;
RT   "Functional genomics of human clear cell sarcoma: genomic,
RT   transcriptomic and chemical biology landscape for clear cell sarcoma.";
RL   Br. J. Cancer 128:1941-1954(2023).
//