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Cellosaurus HP-15a (CVCL_E2TB)

[Text version]
Cell line name HP-15a
Accession CVCL_E2TB
Resource Identification Initiative To cite this cell line use: HP-15a (RRID:CVCL_E2TB)
Comments Population: Caucasian.
Biotechnology: Used in assay systems for the detection of HPA-15a antibodies (PubMed=20812998).
Genetic integration: Method=Transfection/transduction; Gene=HGNC; 21685; CD109 (Note=With p.Tyr703Ser = HPA-15a/Gov(b)).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Gln136fs*13 (c.406_407insC); Zygosity=Homozygous (from parent cell line).
Disease Blast phase chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C9110)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0004 (K-562)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line
Publications

PubMed=20812998; DOI=10.1111/j.1365-2141.2010.08369.x
Hayashi T., Amakishi E., Matsuyama N., Yasui K., Furuta R.A., Hori Y., Fukumori Y., Tanaka S., Curtis B.R., Inoue M., Hirayama F.
Detection of antibodies against human platelet antigens 15a and 15b by using a cell line panel.
Br. J. Haematol. 151:402-404(2010)

Entry history
Entry creation10-Sep-2024
Last entry update10-Sep-2024
Version number1