ID   HP-15a
AC   CVCL_E2TB
RX   PubMed=20812998;
CC   Population: Caucasian.
CC   Biotechnology: Used in assay systems for the detection of HPA-15a antibodies (PubMed=20812998).
CC   Sequence variation: Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Gln136fs*13 (c.406_407insC); Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; 21685; CD109 (Note=With p.Tyr703Ser = HPA-15a/Gov(b)).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C9110; Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
DI   ORDO; Orphanet_521; Chronic myeloid leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0004 ! K-562
SX   Female
AG   53Y
CA   Cancer cell line
DT   Created: 10-09-24; Last updated: 10-09-24; Version: 1
//
RX   PubMed=20812998; DOI=10.1111/j.1365-2141.2010.08369.x;
RA   Hayashi T., Amakishi E., Matsuyama N., Yasui K., Furuta R.A., Hori Y.,
RA   Fukumori Y., Tanaka S., Curtis B.R., Inoue M., Hirayama F.;
RT   "Detection of antibodies against human platelet antigens 15a and 15b
RT   by using a cell line panel.";
RL   Br. J. Haematol. 151:402-404(2010).
//