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Cellosaurus HIO107 (CVCL_E247)

[Text version]
Cell line name HIO107
Synonyms HIO-107; Human Immortal OSE 107
Accession CVCL_E247
Resource Identification Initiative To cite this cell line use: HIO107 (RRID:CVCL_E247)
Comments From: Fox Chase Cancer Center; Philadelphia; USA.
Characteristics: Cell line positive for alternative lengthening of telomeres (ALT+) (PubMed=11082050).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Ovary, surface epithelium; UBERON=UBERON_0001304.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_6E47 (HIO107C6)
Sex of cell Female
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=11082050; DOI=10.1242/jcs.113.24.4577
Grobelny J.V., Godwin A.K., Broccoli D.
ALT-associated PML bodies are present in viable cells and are enriched in cells in the G(2)/M phase of the cell cycle.
J. Cell Sci. 113:4577-4585(2000)

PubMed=11555632; DOI=10.1093/hmg/10.18.1953
Grobelny J.V., Kulp-McEliece M.L., Broccoli D.
Effects of reconstitution of telomerase activity on telomere maintenance by the alternative lengthening of telomeres (ALT) pathway.
Hum. Mol. Genet. 10:1953-1961(2001)

PubMed=12365030; DOI=10.1002/cncr.10870
Capo-Chichi C.D., Smith E.R., Yang D.-H., Roland I.H., Vanderveer L., Cohen C., Hamilton T.C., Godwin A.K., Xu X.-X.
Dynamic alterations of the extracellular environment of ovarian surface epithelial cells in premalignant transformation, tumorigenicity, and metastasis.
Cancer 95:1802-1815(2002)

CLPUB00795
Goodwin A.J.
The nuclear death domain protein p84N5; a candidate breast cancer susceptibility gene.
(In misc. document) Report for award DAMD17-03-1-0312. Defense Technical Information Center document ADA438149; pp.1-26; DTIC; Fort Belvoir; USA (2005)

Cross-references
Encyclopedic resources Wikidata; Q54889567
Entry history
Entry creation22-Oct-2012
Last entry update10-Apr-2025
Version number13