ID   HIO107
AC   CVCL_E247
SY   HIO-107; Human Immortal OSE 107
DR   Wikidata; Q54889567
RX   CelloPub=CLPUB00795;
RX   PubMed=11082050;
RX   PubMed=11555632;
RX   PubMed=12365030;
CC   From: Fox Chase Cancer Center; Philadelphia; USA.
CC   Characteristics: Cell line positive for alternative lengthening of telomeres (ALT+) (PubMed=11082050).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Ovary, surface epithelium; UBERON=UBERON_0001304.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Age unspecified
CA   Transformed cell line
DT   Created: 22-10-12; Last updated: 10-04-25; Version: 13
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RX   CelloPub=CLPUB00795;
RA   Goodwin A.J.;
RT   "The nuclear death domain protein p84N5; a candidate breast cancer
RT   susceptibility gene.";
RL   (In misc. document) Report for award DAMD17-03-1-0312. Defense Technical Information Center document ADA438149; pp.1-26; DTIC; Fort Belvoir; USA (2005).
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RX   PubMed=11082050; DOI=10.1242/jcs.113.24.4577;
RA   Grobelny J.V., Godwin A.K., Broccoli D.;
RT   "ALT-associated PML bodies are present in viable cells and are
RT   enriched in cells in the G(2)/M phase of the cell cycle.";
RL   J. Cell Sci. 113:4577-4585(2000).
//
RX   PubMed=11555632; DOI=10.1093/hmg/10.18.1953;
RA   Grobelny J.V., Kulp-McEliece M.L., Broccoli D.;
RT   "Effects of reconstitution of telomerase activity on telomere
RT   maintenance by the alternative lengthening of telomeres (ALT)
RT   pathway.";
RL   Hum. Mol. Genet. 10:1953-1961(2001).
//
RX   PubMed=12365030; DOI=10.1002/cncr.10870;
RA   Capo-Chichi C.D., Smith E.R., Yang D.-H., Roland I.H., Vanderveer L.,
RA   Cohen C., Hamilton T.C., Godwin A.K., Xu X.-X.;
RT   "Dynamic alterations of the extracellular environment of ovarian
RT   surface epithelial cells in premalignant transformation,
RT   tumorigenicity, and metastasis.";
RL   Cancer 95:1802-1815(2002).
//