Cellosaurus logo
expasy logo

Cellosaurus HyCyte NCI-H520 KO-hPTPRZ1 (CVCL_E1MA)

[Text version]
Cell line name HyCyte NCI-H520 KO-hPTPRZ1
Synonyms hPTPRZ1 knockout NCI-H520
Accession CVCL_E1MA
Resource Identification Initiative To cite this cell line use: HyCyte NCI-H520 KO-hPTPRZ1 (RRID:CVCL_E1MA)
Comments Population: Caucasian.
Doubling time: 48-72 hours (Hysigen=CGKO-M2278).
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:9685; PTPRZ1.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; HGNC:795; ATM; Simple; p.Pro383Ala (c.1147C>G); ClinVar=VCV001001330; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Gly45Valfs*8 (c.134delG); Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Trp146Ter (c.438G>A); ClinVar=VCV000428890; Zygosity=Homozygous (from parent cell line).
Disease Lung squamous cell carcinoma (NCIt: C3493)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1566 (NCI-H520)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Cross-references
Cell line collections (Providers) Hysigen; CGKO-M2278
Entry history
Entry creation10-Sep-2024
Last entry update19-Dec-2024
Version number2