ID   HyCyte NCI-H520 KO-hPTPRZ1
AC   CVCL_E1MA
SY   hPTPRZ1 knockout NCI-H520
DR   Hysigen; CGKO-M2278
CC   Population: Caucasian.
CC   Doubling time: 48-72 hours (Hysigen=CGKO-M2278).
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; 9685; PTPRZ1.
CC   Sequence variation: Mutation; HGNC; 795; ATM; Simple; p.Pro383Ala (c.1147C>G); ClinVar=VCV001001330; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 1787; CDKN2A; Simple; p.Gly45Valfs*8 (c.134delG); Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Trp146Ter (c.438G>A); ClinVar=VCV000428890; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
DI   NCIt; C3493; Lung squamous cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1566 ! NCI-H520
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 10-09-24; Last updated: 10-09-24; Version: 1
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