Cellosaurus WTC11 AAVS1-NEUROG2 SYNJ1-KO (CVCL_E1HU)
| Cell line name | WTC11 AAVS1-NEUROG2 SYNJ1-KO |
|---|---|
| Synonyms | SYNJ1 KO WTC11; SJ1 KO iPSC |
| Accession | CVCL_E1HU |
| Resource Identification Initiative | To cite this cell line use: WTC11 AAVS1-NEUROG2 SYNJ1-KO (RRID:CVCL_E1HU) |
| Comments | Population: Japanese. Characteristics: Using TALEN a PuroR-CAG-rtTA3G-NEUROG2 construct was introduced in both alleles of the AAVS1 safe harbor locus thus providing doxycycline-inducible expression of NEUROG2/NGN2 (from parent cell line). Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:11503; SYNJ1. Genetic integration: Method=TALEN; Gene=HGNC; HGNC:13805; NEUROG2. Genetic integration: Method=TALEN; Gene=UniProtKB; P13249; S.alboniger pac (PuroR). Derived from site: In situ; Leg, skin; UBERON=UBERON_0001511. Cell type: Fibroblast of skin; CL=CL_0002620. |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_C7XJ (Pre-i3Neuron NGN2 iPSC clone 1) |
| Sex of cell | Male |
| Age at sampling | 30Y |
| Category | Induced pluripotent stem cell |
| Publications | PubMed=38635628; DOI=10.1073/pnas.2318943121; PMCID=PMC11047088 |
| Entry history | |
| Entry creation | 10-Sep-2024 |
| Last entry update | 19-Dec-2024 |
| Version number | 2 |