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Cellosaurus UW402 (CVCL_DH81)

[Text version]
Cell line name UW402
Synonyms Uw-402; UW 402
Accession CVCL_DH81
Resource Identification Initiative To cite this cell line use: UW402 (RRID:CVCL_DH81)
Comments Doubling time: 32 +- 0.5 hours (PubMed=31346954).
Disease Medulloblastoma, SHH-activated, TP53-mutant (NCIt: C129442)
Medulloblastoma (ORDO: Orphanet_616)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_8585 ! UW228
CVCL_DH82 ! UW426
Sex of cell Female
Age at sampling 9Y
Category Cancer cell line
Publications

PubMed=20847082; DOI=10.1093/neuonc/noq091; PMCID=PMC3018940
Teider N., Scott D.K., Neiss A., Weeraratne S.D., Amani V.M., Wang Y.-F., Marquez V.E., Cho Y.-J., Pomeroy S.L.
Neuralized1 causes apoptosis and downregulates Notch target genes in medulloblastoma.
Neuro-oncol. 12:1244-1256(2010)

PubMed=22723427; DOI=10.1093/neuonc/nos130; PMCID=PMC3424207
Sikkema A.H., den Dunnen W.F.A., Hulleman E., van Vuurden D.G., Garcia-Manero G., Yang H., Scherpen F.J.G., Kampen K.R., Hoving E.W., Kamps W.A., Diks S.H., Peppelenbosch M.P., de Bont E.S.J.M.
EphB2 activity plays a pivotal role in pediatric medulloblastoma cell adhesion and invasion.
Neuro-oncol. 14:1125-1135(2012)

PubMed=23325114; DOI=10.1007/s10616-012-9529-z; PMCID=PMC3967617
Castro-Gamero A.M., Borges K.S., Lira R.C., Andrade A.F., Fedatto P.F., Cruzeiro G.A.V., Bonfim Silva R., Fontes A.M., Valera E.T., Bobola M.S., Scrideli C.A., Tone L.G.
Chromosomal heterogeneity and instability characterize pediatric medulloblastoma cell lines and affect neoplastic phenotype.
Cytotechnology 65:871-885(2013)

PubMed=27498314; DOI=10.1016/j.jbiotec.2016.07.028
Ivanov D.P., Coyle B., Walker D.A., Grabowska A.M.
In vitro models of medulloblastoma: choosing the right tool for the job.
J. Biotechnol. 236:10-25(2016)

PubMed=27812533; DOI=10.1016/j.dib.2016.10.004; PMCID=PMC5079239
Ivanov D.P., Walker D.A., Coyle B., Grabowska A.M.
Data on the number and frequency of scientific literature citations for established medulloblastoma cell lines.
Data Brief 9:696-698(2016)

PubMed=31346954; DOI=10.1007/s10616-019-00332-3; PMCID=PMC6787134
Bonfim Silva R., Salomao K.B., de Andrade Pimentel T.V.C., de Oliveira Menezes C.C.B., Palma P.V.B., Fontes A.M.
Biological characterization of the UW402, UW473, ONS-76 and DAOY pediatric medulloblastoma cell lines.
Cytotechnology 71:893-903(2019)

Cross-references
Cell line databases/resources cancercelllines; CVCL_DH81
Encyclopedic resources Wikidata; Q54992379
Gene expression databases GEO; GSM482331
Polymorphism and mutation databases Progenetix; CVCL_DH81
Entry history
Entry creation13-Jul-2016
Last entry update05-Oct-2023
Version number9