ID   UW402
AC   CVCL_DH81
SY   Uw-402; UW 402
DR   cancercelllines; CVCL_DH81
DR   GEO; GSM482331
DR   Progenetix; CVCL_DH81
DR   Wikidata; Q54992379
RX   PubMed=20847082;
RX   PubMed=22723427;
RX   PubMed=23325114;
RX   PubMed=27498314;
RX   PubMed=27812533;
RX   PubMed=31346954;
CC   Doubling time: 32 +- 0.5 hours (PubMed=31346954).
DI   NCIt; C129442; Medulloblastoma, SHH-activated, TP53-mutant
DI   ORDO; Orphanet_616; Medulloblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_8585 ! UW228
OI   CVCL_DH82 ! UW426
SX   Female
AG   9Y
CA   Cancer cell line
DT   Created: 13-07-16; Last updated: 05-10-23; Version: 9
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RX   PubMed=20847082; DOI=10.1093/neuonc/noq091;
RA   Teider N., Scott D.K., Neiss A., Weeraratne S.D., Amani V.M., Wang Y.-F.,
RA   Marquez V.E., Cho Y.-J., Pomeroy S.L.;
RT   "Neuralized1 causes apoptosis and downregulates Notch target genes in
RT   medulloblastoma.";
RL   Neuro-oncol. 12:1244-1256(2010).
//
RX   PubMed=22723427; DOI=10.1093/neuonc/nos130;
RA   Sikkema A.H., den Dunnen W.F.A., Hulleman E., van Vuurden D.G.,
RA   Garcia-Manero G., Yang H., Scherpen F.J.G., Kampen K.R., Hoving E.W.,
RA   Kamps W.A., Diks S.H., Peppelenbosch M.P., de Bont E.S.J.M.;
RT   "EphB2 activity plays a pivotal role in pediatric medulloblastoma cell
RT   adhesion and invasion.";
RL   Neuro-oncol. 14:1125-1135(2012).
//
RX   PubMed=23325114; DOI=10.1007/s10616-012-9529-z;
RA   Castro-Gamero A.M., Borges K.S., Lira R.C., Andrade A.F.,
RA   Fedatto P.F., Cruzeiro G.A.V., Bonfim Silva R., Fontes A.M.,
RA   Valera E.T., Bobola M.S., Scrideli C.A., Tone L.G.;
RT   "Chromosomal heterogeneity and instability characterize pediatric
RT   medulloblastoma cell lines and affect neoplastic phenotype.";
RL   Cytotechnology 65:871-885(2013).
//
RX   PubMed=27498314; DOI=10.1016/j.jbiotec.2016.07.028;
RA   Ivanov D.P., Coyle B., Walker D.A., Grabowska A.M.;
RT   "In vitro models of medulloblastoma: choosing the right tool for the
RT   job.";
RL   J. Biotechnol. 236:10-25(2016).
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RX   PubMed=27812533; DOI=10.1016/j.dib.2016.10.004;
RA   Ivanov D.P., Walker D.A., Coyle B., Grabowska A.M.;
RT   "Data on the number and frequency of scientific literature citations
RT   for established medulloblastoma cell lines.";
RL   Data Brief 9:696-698(2016).
//
RX   PubMed=31346954; DOI=10.1007/s10616-019-00332-3;
RA   Bonfim Silva R., Salomao K.B., de Andrade Pimentel T.V.C.,
RA   de Oliveira Menezes C.C.B., Palma P.V.B., Fontes A.M.;
RT   "Biological characterization of the UW402, UW473, ONS-76 and DAOY
RT   pediatric medulloblastoma cell lines.";
RL   Cytotechnology 71:893-903(2019).
//