Cellosaurus H4L7.5c2 (CVCL_DC28)
| Cell line name | H4L7.5c2 |
|---|---|
| Accession | CVCL_DC28 |
| Resource Identification Initiative | To cite this cell line use: H4L7.5c2 (RRID:CVCL_DC28) |
| Comments | Biotechnology: Cell line developed for CALUX (Chemically Activated LUciferase eXpression) bioassay. CALUX is used for rapid screening of samples for the presence of dioxin/TCDD-like compounds and AhR agonists/antagonists. Characteristics: Acts through the activation of a luciferase reporter gene under the control of dioxin-response elements (DREs). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Firefly luciferase. Derived from site: In situ; Liver; UBERON=UBERON_0002107. |
| Disease | Rat hepatocellular carcinoma (NCIt: C60416) |
| Species of origin | Rattus norvegicus (Rat)
(NCBI Taxonomy: 10116)
Breed/subspecies: AxC; RS=RS:0000369. |
| Hierarchy | Parent: CVCL_0284 (H4-II-E) |
| Sex of cell | Male |
| Category | Cancer cell line |
| Publications | PubMed=26366531; DOI=10.1021/acs.est.5b02906; PMCID=PMC4772899 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q54872159 |
| Entry history | |
| Entry creation | 13-Jul-2016 |
| Last entry update | 10-Sep-2024 |
| Version number | 9 |