ID   H4L7.5c2
AC   CVCL_DC28
DR   Wikidata; Q54872159
RX   PubMed=26366531;
CC   Biotechnology: Cell line developed for CALUX (Chemically Activated LUciferase eXpression) bioassay. CALUX is used for rapid screening of samples for the presence of dioxin/TCDD-like compounds and AhR agonists/antagonists.
CC   Characteristics: Acts through the activation of a luciferase reporter gene under the control of dioxin-response elements (DREs).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Firefly luciferase.
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
CC   Breed/subspecies: AxC; RS=RS:0000369.
DI   NCIt; C60416; Rat hepatocellular carcinoma
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
HI   CVCL_0284 ! H4-II-E
SX   Male
CA   Cancer cell line
DT   Created: 13-07-16; Last updated: 10-09-24; Version: 9
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RX   PubMed=26366531; DOI=10.1021/acs.est.5b02906; PMCID=PMC4772899;
RA   Brennan J.C., He G.-C., Tsutsumi T., Zhao J., Wirth E., Fulton M.H.,
RA   Denison M.S.;
RT   "Development of species-specific Ah receptor-responsive third
RT   generation CALUX cell lines with enhanced responsiveness and improved
RT   detection limits.";
RL   Environ. Sci. Technol. 49:11903-11912(2015).
//