Cellosaurus cell line Ubigene HT-29 ETHE1 KO (CVCL

Cross-references
Cell line name	Ubigene HT-29 ETHE1 KO
Synonyms	ETHE1 Knockout cell line (HT-29)
Accession	CVCL_D9WG
Resource Identification Initiative	To cite this cell line use: Ubigene HT-29 ETHE1 KO (RRID:CVCL_D9WG)
Comments	Population: Caucasian. Knockout cell: Method=CRISPR/Cas9; HGNC; 23287; ETHE1. Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations	Mutation; HGNC; 583; APC; Simple; p.Glu853Ter (c.2557G>T); ClinVar=VCV001071632; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; 583; APC; Simple; p.Thr1556Asnfs*3 (c.4666dupA) (c.4666_4667insA); ClinVar=VCV000428112; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; 8975; PIK3CA; Simple; p.Pro449Thr (c.1345C>A); ClinVar=VCV001333250; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; 6770; SMAD4; Simple; p.Gln311Ter (c.931C>T); ClinVar=VCV000230663; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
Disease	Colon adenocarcinoma (NCIt: C4349)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0320 (HT-29)
Sex of cell	Female
Age at sampling	44Y
Category	Cancer cell line
Cell line collections (Providers)	Ubigene; YKO-H1125
Entry history
Entry creation	10-Sep-2024
Last entry update	10-Sep-2024
Version number	1