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Cellosaurus Ubigene HT-1080 RIPK1 KO (CVCL_D9WE)

[Text version]
Cell line name Ubigene HT-1080 RIPK1 KO
Synonyms RIPK1 Knockout cell line (HT-1080)
Accession CVCL_D9WE
Resource Identification Initiative To cite this cell line use: Ubigene HT-1080 RIPK1 KO (RRID:CVCL_D9WE)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:10019; RIPK1.
Derived from site: In situ; Bone, pelvis, acetabulum; UBERON=UBERON_0001269.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:5382; IDH1; Simple; p.Arg132Cys (c.394C>T); ClinVar=VCV000375891; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
Disease Fibrosarcoma (NCIt: C3043)
Fibrosarcoma (ORDO: Orphanet_2030)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0317 (HT-1080)
Sex of cell Male
Age at sampling 35Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Ubigene; YKO-HJ060
Entry history
Entry creation10-Sep-2024
Last entry update19-Dec-2024
Version number2