Cellosaurus cell line Ubigene HT-1080 AIFM2 KO (CVCL

Cross-references
Cell line name	Ubigene HT-1080 AIFM2 KO
Synonyms	AIFM2 Knockout cell line (HT-1080)
Accession	CVCL_D9WD
Resource Identification Initiative	To cite this cell line use: Ubigene HT-1080 AIFM2 KO (RRID:CVCL_D9WD)
Comments	Population: Caucasian. Knockout cell: Method=CRISPR/Cas9; HGNC; 21411; AIFM2. Derived from site: In situ; Bone, pelvis, acetabulum; UBERON=UBERON_0001269.
Sequence variations	Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; 5382; IDH1; Simple; p.Arg132Cys (c.394C>T); ClinVar=VCV000375891; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
Disease	Fibrosarcoma (NCIt: C3043) Fibrosarcoma (ORDO: Orphanet_2030)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0317 (HT-1080)
Sex of cell	Male
Age at sampling	35Y
Category	Cancer cell line
Cell line collections (Providers)	Ubigene; YKO-H363
Entry history
Entry creation	10-Sep-2024
Last entry update	10-Sep-2024
Version number	1