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Cellosaurus Ubigene A-549/DDP UCA1 KO (CVCL_D8DM)

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Cell line name Ubigene A-549/DDP UCA1 KO
Synonyms UCA1 Knockout cell line (A549/DDP)
Accession CVCL_D8DM
Resource Identification Initiative To cite this cell line use: Ubigene A-549/DDP UCA1 KO (RRID:CVCL_D8DM)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; 37126; UCA1.
Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C0W4 (A549/DDP)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Ubigene; YKO-HJ080
Entry history
Entry creation10-Sep-2024
Last entry update10-Sep-2024
Version number1