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Cellosaurus A549/DDP (CVCL_C0W4)

[Text version]
Cell line name A549/DDP
Accession CVCL_C0W4
Resource Identification Initiative To cite this cell line use: A549/DDP (RRID:CVCL_C0W4)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP).
Transfected with: UniProtKB; P42212; GFP.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0023 (A-549)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Publications

PubMed=28114404; DOI=10.1371/journal.pone.0170609
Fang Y.-N., Zhang C., Wu T., Wang Q., Liu J.-H., Dai P.-G.
Transcriptome sequencing reveals key pathways and genes associated with cisplatin resistance in lung adenocarcinoma A549 cells.
PLoS ONE 12:E0170609-E0170609(2017)

Cross-references
Cell line collections (Providers) CLS; 305047
Cell line databases/resources cancercelllines; CVCL_C0W4
Encyclopedic resources Wikidata; Q114310532
Entry history
Entry creation22-Sep-2022
Last entry update05-Oct-2023
Version number5