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Cellosaurus A549/DDP (CVCL_C0W4)

[Text version]
Cell line name A549/DDP
Accession CVCL_C0W4
Resource Identification Initiative To cite this cell line use: A549/DDP (RRID:CVCL_C0W4)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0023 (A-549)
Children:
CVCL_D8DM (Ubigene A-549/DDP UCA1 KO)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
STR profile Source(s): CLS=305047

Markers:
AmelogeninX,Y
CSF1PO10,12
D2S133824
D3S135816
D5S81811
D6S104311,13
D7S8208,11
D8S117913,14
D12S39118
D13S31711
D16S53911,12
D18S5114,17
D19S43313
D21S1129
FGA23
Penta D9
Penta E7,11
TH018,9.3
TPOX8,11
vWA14

Run an STR similarity search on this cell line
Publications

PubMed=28114404; DOI=10.1371/journal.pone.0170609; PMCID=PMC5256872
Fang Y.-N., Zhang C., Wu T., Wang Q., Liu J.-H., Dai P.-G.
Transcriptome sequencing reveals key pathways and genes associated with cisplatin resistance in lung adenocarcinoma A549 cells.
PLoS ONE 12:E0170609-E0170609(2017)

Cross-references
Cell line collections (Providers) CLS; 305047
Cell line databases/resources cancercelllines; CVCL_C0W4
Encyclopedic resources Wikidata; Q114310532
Entry history
Entry creation22-Sep-2022
Last entry update10-Sep-2024
Version number6