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Cellosaurus U2OS-GFP-STAT1 (CVCL_D7E1)

[Text version]
Cell line name U2OS-GFP-STAT1
Accession CVCL_D7E1
Resource Identification Initiative To cite this cell line use: U2OS-GFP-STAT1 (RRID:CVCL_D7E1)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; 11362; STAT1.
Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
Sequence variations
  • Mutation; HGNC; 9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0042 (U2OS)
Children:
CVCL_D7E2 (U2OS-GFP-STAT1/CSF-1R)
Sex of cell Female
Age at sampling 15Y
Category Cancer cell line
Publications

Patent=US9683988
Wang L.-L., Yang S.-Q., Long L., Xiao J.-H., Li S.
Cell model and method for screening c-Fms kinase inhibitors.
Patent number US9683988, 20-Jun-2017

Entry history
Entry creation10-Sep-2024
Last entry update10-Sep-2024
Version number1