Cellosaurus logo
expasy logo

Cellosaurus BIONi010C-48 (CVCL_D6PB)

[Text version]
Cell line name BIONi010C-48
Synonyms BIONi010-C hMDR1; BIONi010-C CAG_hMDR1 in AAVS1 cl. #B31-75
Accession CVCL_D6PB
Resource Identification Initiative To cite this cell line use: BIONi010C-48 (RRID:CVCL_D6PB)
Comments From: Bioneer A/S; Horsholm; Denmark.
Population: African.
Characteristics: Using TALEN a ABCB1/MDR1-neo construct was introduced in both alleles of the AAVS1 safe harbor locus (PubMed=38364505).
Genetic integration: Method=TALEN; Gene=HGNC; 40; ABCB1.
Genetic integration: Method=TALEN; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1E68 (BIONi010-C)
Sex of cell Male
Age at sampling 18Y
Category Induced pluripotent stem cell
Publications

PubMed=38364505; DOI=10.1016/j.scr.2024.103348
Nielsen A.K.R., Lilieholm-Rongren L., Schmid B., Holst B., Brodin B., Saaby L.
Generation of an iPSC-line (BIONi010C-48) with restored P-glycoprotein functionality following transfection with the human MDR1 gene in the AAVS1 locus.
Stem Cell Res. 76:103348-103348(2024)

Cross-references
Cell line databases/resources hPSCreg; BIONi010-C-48
Biological sample resources BioSamples; SAMEA115286272
Entry history
Entry creation10-Sep-2024
Last entry update10-Sep-2024
Version number1