Cellosaurus cell line HyCyte HT-1080 KO-hSMARCA4 (CVCL

Cross-references
Cell line name	HyCyte HT-1080 KO-hSMARCA4
Synonyms	hSMARCA4 knockout HT-1080
Accession	CVCL_D6BS
Resource Identification Initiative	To cite this cell line use: HyCyte HT-1080 KO-hSMARCA4 (RRID:CVCL_D6BS)
Comments	Population: Caucasian. Doubling time: 24-48 hours (Hysigen=CGKO-M2389). Knockout cell: Method=CRISPR/Cas9; HGNC; 11100; SMARCA4. Derived from site: In situ; Bone, pelvis, acetabulum; UBERON=UBERON_0001269.
Sequence variations	Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; 5382; IDH1; Simple; p.Arg132Cys (c.394C>T); ClinVar=VCV000375891; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
Disease	Fibrosarcoma (NCIt: C3043) Fibrosarcoma (ORDO: Orphanet_2030)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0317 (HT-1080)
Sex of cell	Male
Age at sampling	35Y
Category	Cancer cell line
Cell line collections (Providers)	Hysigen; CGKO-M2389
Encyclopedic resources	Wikidata; Q127382029
Entry history
Entry creation	02-May-2024
Last entry update	10-Sep-2024
Version number	2