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Cellosaurus HyCyte HT1080 KO-hSMARCA4 (CVCL_D6BS)

[Text version]
Cell line name HyCyte HT1080 KO-hSMARCA4
Synonyms hSMARCA4 knockout HT1080
Accession CVCL_D6BS
Resource Identification Initiative To cite this cell line use: HyCyte HT1080 KO-hSMARCA4 (RRID:CVCL_D6BS)
Comments Population: Caucasian.
Doubling time: 24-48 hours (Hysigen=CGKO-M2389).
Knockout cell: Method=CRISPR/Cas9; HGNC; 11100; SMARCA4.
Derived from site: In situ; Bone, pelvis, acetabulum; UBERON=UBERON_0001269.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 5382; IDH1; Simple; p.Arg132Cys (c.394C>T); ClinVar=VCV000375891; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
Disease Fibrosarcoma (NCIt: C3043)
Fibrosarcoma (ORDO: Orphanet_2030)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0317 (HT-1080)
Sex of cell Male
Age at sampling 35Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Hysigen; CGKO-M2389
Entry history
Entry creation02-May-2024
Last entry update02-May-2024
Version number1