Cellosaurus cell line KH-300 (CVCL

Cellosaurus KH-300 (CVCL_D5AW)

[Text version]

Cell line name

KH-300

Synonyms

KH300

Accession

CVCL_D5AW

Resource Identification Initiative

To cite this cell line use: KH-300 (RRID:CVCL_D5AW)

Comments

Population: Caucasian.
Doubling time: 50 hours (CelloPub=CLPUB00761).
Selected for resistance to: ChEBI; CHEBI:44423; Hydroxyurea.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.

Sequence variations

Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Gln136fs*13 (c.406_407insC); Zygosity=Homozygous (from parent cell line).

Disease

Blast phase chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C9110)
Chronic myeloid leukemia (ORDO: Orphanet_521)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_D5D1 (KH-250)
Children:

CVCL_D5D2 (KH-375)

Sex of cell

Female

Age at sampling

53Y