Cellosaurus cell line IU-TAB-1 (CVCL

Cellosaurus IU-TAB-1 (CVCL_D551)

Cross-references
Cell line name	IU-TAB-1
Synonyms	IU-TAB1
Accession	CVCL_D551
Resource Identification Initiative	To cite this cell line use: IU-TAB-1 (RRID:CVCL_D551)
Comments	Doubling time: 48 hours (PubMed=22926645). Omics: Transcriptome analysis by microarray. Donor information: Established from a 35 packs per year smoker (PubMed=22926645). Derived from site: In situ; Mediastinum; UBERON=UBERON_0003728. Cell type: Epithelial cell of thymus; CL=CL_0002293.
Sequence variations	Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (PubMed=27117832).
Disease	Thymoma type AB (NCIt: C6885) Thymoma (ORDO: Orphanet_99867)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	53Y
Category	Cancer cell line
Publications	PubMed=22926645; DOI=10.1038/labinvest.2012.115 Gokmen-Polar Y., Sanders K.L., Goswami C.P., Cano O.D., Zaheer N.A., Jain R.K., Kesler K.A., Nelson R.P. Jr., Vance G.H., Smith D., Li L., Cardoso A.A., Badve S., Loehrer P.J. Sr., Sledge G.W. Jr. Establishment and characterization of a novel cell line derived from human thymoma AB tumor. Lab. Invest. 92:1564-1573(2012) PubMed=27117832; DOI=10.1016/j.jtho.2016.04.013; PMCID=PMC5319212 Alberobello A.T., Wang Y.-S., Beerkens F.J., Conforti F., McCutcheon J.N., Rao G.-H., Raffeld M., Liu J., Rahhal R., Zhang Y.-W., Giaccone G. PI3K as a potential therapeutic target in thymic epithelial tumors. J. Thorac. Oncol. 11:1345-1356(2016)
Cell line databases/resources	cancercelllines; CVCL_D551
Encyclopedic resources	Wikidata; Q54898377
Polymorphism and mutation databases	Cosmic; 2663904
Entry history
Entry creation	22-Oct-2012
Last entry update	19-Dec-2024
Version number	19