ID   IU-TAB-1
AC   CVCL_D551
SY   IU-TAB1
DR   cancercelllines; CVCL_D551
DR   Cosmic; 2663904
DR   Wikidata; Q54898377
RX   PubMed=22926645;
RX   PubMed=27117832;
CC   Doubling time: 48 hours (PubMed=22926645).
CC   Sequence variation: Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (PubMed=27117832).
CC   Omics: Transcriptome analysis by microarray.
CC   Donor information: Established from a 35 packs per year smoker (PubMed=22926645).
CC   Derived from site: In situ; Mediastinum; UBERON=UBERON_0003728.
CC   Cell type: Epithelial cell of thymus; CL=CL_0002293.
DI   NCIt; C6885; Thymoma type AB
DI   ORDO; Orphanet_99867; Thymoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   53Y
CA   Cancer cell line
DT   Created: 22-10-12; Last updated: 19-12-24; Version: 19
//
RX   PubMed=22926645; DOI=10.1038/labinvest.2012.115;
RA   Gokmen-Polar Y., Sanders K.L., Goswami C.P., Cano O.D., Zaheer N.A.,
RA   Jain R.K., Kesler K.A., Nelson R.P. Jr., Vance G.H., Smith D., Li L.,
RA   Cardoso A.A., Badve S., Loehrer P.J. Sr., Sledge G.W. Jr.;
RT   "Establishment and characterization of a novel cell line derived from
RT   human thymoma AB tumor.";
RL   Lab. Invest. 92:1564-1573(2012).
//
RX   PubMed=27117832; DOI=10.1016/j.jtho.2016.04.013; PMCID=PMC5319212;
RA   Alberobello A.T., Wang Y.-S., Beerkens F.J., Conforti F.,
RA   McCutcheon J.N., Rao G.-H., Raffeld M., Liu J., Rahhal R., Zhang Y.-W.,
RA   Giaccone G.;
RT   "PI3K as a potential therapeutic target in thymic epithelial tumors.";
RL   J. Thorac. Oncol. 11:1345-1356(2016).
//