Cellosaurus U2OS SP2 CL1 (CVCL_D4XX)
Cell line name | U2OS SP2 CL1 |
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Accession | CVCL_D4XX |
Resource Identification Initiative | To cite this cell line use: U2OS SP2 CL1 (RRID:CVCL_D4XX) |
Comments | Population: Caucasian. Characteristics: Transfected with two constructs, one containing the PEX3 peroxisome targeting sequence (PTS) fused to RFP and FKBP (PTS-RFP-FKBP) and the other to the FKBP-rapamycin-binding (FRB) domain of mTOR linked to the N-terminal half of mouse BicD2 (BicD2N) and GFP (GFP-BicD2N-FRB) (PubMed=32436764). Transfected with: HGNC; 3711; FKBP1A. Transfected with: HGNC; 3942; MTOR (with Met1_Arg2018del and Gln2114_Trp2549del = FRB). Transfected with: MGI; MGI:1924145; Bicd2 (with Arg401_Leu820del = Bicd2N). Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP). Transfected with: UniProtKB; Q9U6Y8; Discosoma sp. red fluorescent protein drFP583 (DsRed, RFP). Transfected with: UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Transfected with: UniProtKB; P00552; Transposon Tn5 neo. Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979. |
Sequence variations |
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Disease | Osteosarcoma (NCIt: C9145) Osteosarcoma (ORDO: Orphanet_668) |
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
Hierarchy | Parent: CVCL_0042 (U2OS) |
Sex of cell | Female |
Age at sampling | 15Y |
Category | Cancer cell line |
Publications | PubMed=32436764; DOI=10.1177/2472555220920581 |
Entry history | |
Entry creation | 02-May-2024 |
Last entry update | 02-May-2024 |
Version number | 1 |