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Cellosaurus G1E-ER2 (CVCL_D4C9)

[Text version]
Cell line name G1E-ER2
Accession CVCL_D4C9
Resource Identification Initiative To cite this cell line use: G1E-ER2 (RRID:CVCL_D4C9)
Comments Characteristics: Transfected with a GATA-1-ER construct (Gata1 fused to the ligand-binding domains of ESR1).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:3467; ESR1 (Note=Ligand-binding domain).
Genetic integration: Method=Transduction; Gene=MGI; MGI:95661; Gata1.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:990; BCL2.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Breed/subspecies: 129S/SvEv-Gpi1<c>.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_D046 (G1E)
Sex of cell Male
Age at sampling Blastocyst stage
Category Embryonic stem cell
Publications

PubMed=10381501; DOI=10.1182/blood.V94.1.87.413k41_87_96
Gregory T., Yu C., Ma A., Orkin S.H., Blobel G.A., Weiss M.J.
GATA-1 and erythropoietin cooperate to promote erythroid cell survival by regulating bcl-xL expression.
Blood 94:87-96(1999)

Cross-references
Encyclopedic resources Wikidata; Q127380864
Entry history
Entry creation30-Jan-2024
Last entry update19-Dec-2024
Version number3