| Cell line name |
ARSI |
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| Accession |
CVCL_D3X9 |
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| Resource Identification Initiative |
To cite this cell line use: ARSI (RRID:CVCL_D3X9) |
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| Comments |
Characteristics: Established from a xenograft that was obtain by transplantation of the tumor cells in female immunodeficient NSG (NOD.Cg-Prkdc[scid] l2rg[tm1Wjll]/SzJ) mouse (PubMed=36084691).
Doubling time: ~24 hours (PubMed=36084691).
Omics: SNP array analysis.
Derived from site: In situ; Leg, skin; UBERON=UBERON_0001511. |
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| Sequence variations |
- Gene deletion; HGNC; HGNC:6119; IRF4; Zygosity=Heterozygous (PubMed=36084691).
- Mutation; HGNC; HGNC:1699; CD79B; Simple; p.Tyr196Cys (c.587A>G); Zygosity=Heterozygous (PubMed=36084691).
- Mutation; HGNC; HGNC:6119; IRF4; Simple; p.Gln60Lys (c.178C>A); Zygosity=Heterozygous (PubMed=36084691).
- Mutation; HGNC; HGNC:6119; IRF4; Simple; p.Ser104Arg (c.312C>A); Zygosity=Heterozygous (PubMed=36084691).
- Mutation; HGNC; HGNC:7562; MYD88; Simple; p.Leu265Pro (c.794T>C); Zygosity=Heterozygous (PubMed=36084691).
- Mutation; HGNC; HGNC:8986; PIM1; Simple; p.Glu123Gln (c.367G>C); Zygosity=Heterozygous (PubMed=36084691).
- Mutation; HGNC; HGNC:8986; PIM1; Simple; p.Pro124Ser (c.370C>T); Zygosity=Heterozygous (PubMed=36084691).
- Mutation; HGNC; HGNC:8986; PIM1; Simple; p.His159Tyr (c.475C>T); Zygosity=Heterozygous (PubMed=36084691).
- Mutation; HGNC; HGNC:8986; PIM1; Simple; p.Ser166Phe (c.497C>T); Zygosity=Homozygous (PubMed=36084691).
- Mutation; HGNC; HGNC:8986; PIM1; Simple; p.Leu220Val (c.658C>G); Zygosity=Homozygous (PubMed=36084691).
- Mutation; HGNC; HGNC:8986; PIM1; Simple; p.Glu226Lys (c.676G>A); Zygosity=Homozygous (PubMed=36084691).
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| Disease |
Primary cutaneous diffuse large B-cell lymphoma, leg type (NCIt: C45194) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Sex of cell |
Female |
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| Age at sampling |
85Y |
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| Category |
Cancer cell line |
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| Publications | PubMed=36084691; DOI=10.1016/j.jid.2022.08.043
Prochazkova-Carlotti M., Gros A., Richard E., Cherrier F., Laharanne E., Idrissi Y., Baron C., Poglio S., Ducharme O., Menguy S., Pham-Ledard A., Beylot-Barry M., Merlio J.-P., Bresson-Bepoldin L.
Patient-derived xenograft and cell line models of human primary cutaneous diffuse large B-cell lymphoma-leg type.
J. Invest. Dermatol. 143:340-344.e6(2023) |
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| Cross-references |
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| Encyclopedic resources |
Wikidata; Q127380237
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| Entry history |
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| Entry creation | 30-Jan-2024 |
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| Last entry update | 19-Dec-2024 |
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| Version number | 3 |
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