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Cellosaurus ZR/HERc 1E (CVCL_D3WB)

[Text version]
Cell line name ZR/HERc 1E
Accession CVCL_D3WB
Resource Identification Initiative To cite this cell line use: ZR/HERc 1E (RRID:CVCL_D3WB)
Comments Population: Caucasian.
Characteristics: Expresses EGFR under the control of HSV-1 TK promoter (PubMed=1516065).
Transfected with: HGNC; 3236; EGFR.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; 5173; HRAS; Simple; p.Glu162Lys (c.484G>A); ClinVar=VCV001034833; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 9588; PTEN; Simple; p.Leu108Arg (c.323T>G); Zygosity=Homozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0588 (ZR-75-1)
Sex of cell Female
Age at sampling 63Y
Category Cancer cell line

van Agthoven T., van Agthoven T.L.A., Portengen H., Foekens J.A., Dorssers L.C.J.
Ectopic expression of epidermal growth factor receptors induces hormone independence in ZR-75-1 human breast cancer cells.
Cancer Res. 52:5082-5088(1992)

Entry history
Entry creation30-Jan-2024
Last entry update30-Jan-2024
Version number1