ID   ZR/HERc 1E
AC   CVCL_D3WB
RX   PubMed=1516065;
CC   Population: Caucasian.
CC   Characteristics: Expresses EGFR under the control of HSV-1 TK promoter (PubMed=1516065).
CC   Sequence variation: Mutation; HGNC; 5173; HRAS; Simple; p.Glu162Lys (c.484G>A); ClinVar=VCV001034833; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 9588; PTEN; Simple; p.Leu108Arg (c.323T>G); Zygosity=Homozygous (from parent cell line).
CC   Transfected with: HGNC; 3236; EGFR.
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
DI   NCIt; C4194; Invasive breast carcinoma of no special type
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0588 ! ZR-75-1
SX   Female
AG   63Y
CA   Cancer cell line
DT   Created: 30-01-24; Last updated: 30-01-24; Version: 1
//
RX   PubMed=1516065;
RA   van Agthoven T., van Agthoven T.L.A., Portengen H., Foekens J.A.,
RA   Dorssers L.C.J.;
RT   "Ectopic expression of epidermal growth factor receptors induces
RT   hormone independence in ZR-75-1 human breast cancer cells.";
RL   Cancer Res. 52:5082-5088(1992).
//