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Cellosaurus Zt/g4 (CVCL_D3UL)

[Text version]
Cell line name Zt/g4
Accession CVCL_D3UL
Resource Identification Initiative To cite this cell line use: Zt/g4 (RRID:CVCL_D3UL)
Comments Biotechnology: The monoclonal antibody produced by this hybridoma was used to prepare a humanized monomethyl auristatin E conjugated (Zt/g4-MMAE) therapeutic antibody whcih is evaluated for the treatment of pancreatic cancer.
Monoclonal antibody isotype: IgG1, lambda.
Monoclonal antibody target: UniProtKB; Q04912; Human MST1R/CD136.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_2199 (Sp2/0-Ag14)
Category Hybridoma
Publications

PubMed=16880737; DOI=10.4161/cbt.5.9.3073
Yao H.-P., Luo Y.-L., Feng L., Cheng L.-F., Lu Y., Li W., Wang M.-H.
Agonistic monoclonal antibodies potentiate tumorigenic and invasive activities of splicing variant of the RON receptor tyrosine kinase.
Cancer Biol. Ther. 5:1179-1186(2006)

PubMed=21749705; DOI=10.1186/1476-4598-10-82; PMCID=PMC3142532
Yao H.-P., Zhou Y.-Q., Ma Q., Guin S., Padhye S.S., Zhang R.-W., Wang M.-H.
The monoclonal antibody Zt/f2 targeting RON receptor tyrosine kinase as potential therapeutics against tumor growth-mediated by colon cancer cells.
Mol. Cancer 10:82.1-82.12(2011)

Cross-references
Encyclopedic resources Wikidata; Q127384796
Entry history
Entry creation30-Jan-2024
Last entry update10-Sep-2024
Version number2