ID   Zt/g4
AC   CVCL_D3UL
DR   Wikidata; Q127384796
RX   PubMed=16880737;
RX   PubMed=21749705;
CC   Biotechnology: The monoclonal antibody produced by this hybridoma was used to prepare a humanized monomethyl auristatin E conjugated (Zt/g4-MMAE) therapeutic antibody whcih is evaluated for the treatment of pancreatic cancer.
CC   Monoclonal antibody isotype: IgG1, lambda.
CC   Monoclonal antibody target: UniProtKB; Q04912; Human MST1R/CD136.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_2199 ! Sp2/0-Ag14
CA   Hybridoma
DT   Created: 30-01-24; Last updated: 10-09-24; Version: 2
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RX   PubMed=16880737; DOI=10.4161/cbt.5.9.3073;
RA   Yao H.-P., Luo Y.-L., Feng L., Cheng L.-F., Lu Y., Li W., Wang M.-H.;
RT   "Agonistic monoclonal antibodies potentiate tumorigenic and invasive
RT   activities of splicing variant of the RON receptor tyrosine kinase.";
RL   Cancer Biol. Ther. 5:1179-1186(2006).
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RX   PubMed=21749705; DOI=10.1186/1476-4598-10-82; PMCID=PMC3142532;
RA   Yao H.-P., Zhou Y.-Q., Ma Q., Guin S., Padhye S.S., Zhang R.-W.,
RA   Wang M.-H.;
RT   "The monoclonal antibody Zt/f2 targeting RON receptor tyrosine kinase
RT   as potential therapeutics against tumor growth-mediated by colon
RT   cancer cells.";
RL   Mol. Cancer 10:82.1-82.12(2011).
//