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Cellosaurus HeLa-MAGI-CCR5 (CVCL_D260)

[Text version]
Cell line name HeLa-MAGI-CCR5
Synonyms HeLa-CD4-CCR5; MAGI-CCR5; MAGI-CCR-5
Accession CVCL_D260
Resource Identification Initiative To cite this cell line use: HeLa-MAGI-CCR5 (RRID:CVCL_D260)
Comments Population: African American.
Characteristics: Can be used to can be used to screen for anti-HIV-1 drugs (PubMed=9094670).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1606; CCR5.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1678; CD4.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00722; Escherichia coli beta-galactosidase (lacZ).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_D259 (HeLa-MAGI)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Web pages Info; IdeaConnection; -; https://www.ideaconnection.com/patents/3382-MAGI-CCR5-Cells.html
Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/m/cell-lines-detail-559.html
Publications

PubMed=9094670; DOI=10.1128/JVI.71.5.3932-3939.1997; PMCID=PMC191545
Chackerian B., Long E.M., Luciw P.A., Overbaugh J.
Human immunodeficiency virus type 1 coreceptors participate in postentry stages in the virus replication cycle and function in simian immunodeficiency virus infection.
J. Virol. 71:3932-3939(1997)

PubMed=9201229; DOI=10.1006/viro.1997.8606
Vodicka M.A., Goh W.C., Wu L.I., Rogel M.E., Bartz S.R., Schweickart V.L., Raport C.J., Emerman M.
Indicator cell lines for detection of primary strains of human and simian immunodeficiency viruses.
Virology 233:193-198(1997)

PubMed=11158746; DOI=10.1128/AAC.45.2.495-501.2001; PMCID=PMC90318
Hachiya A., Aizawa-Matsuoka S., Tanaka M., Takahashi Y., Ida S., Gatanaga H., Hirabayashi Y., Kojima A., Tatsumi M., Oka S.
Rapid and simple phenotypic assay for drug susceptibility of human immunodeficiency virus type 1 using CCR5-expressing HeLa/CD4(+) cell clone 1-10 (MAGIC-5).
Antimicrob. Agents Chemother. 45:495-501(2001)

Cross-references
Cell line collections (Providers) BEI_Resources; ARP-3522
Cell line databases/resources CLO; CLO_0037219
Anatomy/cell type resources BTO; BTO_0003587
Encyclopedic resources Wikidata; Q54882720
Entry history
Entry creation22-Oct-2012
Last entry update10-Apr-2025
Version number25