Cellosaurus HeLa-MAGI (CVCL_D259)
| Cell line name | HeLa-MAGI | ||||||||||||||||||
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| Synonyms | HeLa MAGI; HeLa Magi; MAGI; HeLa-CD4-LTR-beta-gal; HeLa-CD4-LTR/beta-gal; CD4-LTR/beta-gal; HeLa-Multinuclear Activation of a Galactosidase Indicator | ||||||||||||||||||
| Accession | CVCL_D259 | ||||||||||||||||||
| Resource Identification Initiative | To cite this cell line use: HeLa-MAGI (RRID:CVCL_D259) | ||||||||||||||||||
| Comments | Population: African American. Characteristics: Transfected with a construct pJK2 containing the HIV-1 LTR fused to a lacZ reporter gene that contains a MPKKKRK N-terminal sequence directing it to the nucleus (PubMed=1548759). Virology: Can be used to determine quantitatively the titer of laboratory-adapted HIV-1 strains (PubMed=1548759). Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1678; CD4. Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo. Genetic integration: Method=Transfection; Gene=UniProtKB; P00722; Escherichia coli beta-galactosidase (lacZ). Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18). Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002. | ||||||||||||||||||
| Disease | Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677) | ||||||||||||||||||
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||
| Hierarchy | Parent: CVCL_E8AI (HeLa-CD4) Children:
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| Sex of cell | Female | ||||||||||||||||||
| Age at sampling | 30Y6M | ||||||||||||||||||
| Category | Cancer cell line | ||||||||||||||||||
| STR profile | Source(s): RCB=RCB2356 Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
| Publications | PubMed=1548759; DOI=10.1128/JVI.66.4.2232-2239.1992; PMCID=PMC289016 | ||||||||||||||||||
| Cross-references | |||||||||||||||||||
| Cell line collections (Providers) | BEI_Resources; ARP-1470
RCB; RCB2356 | ||||||||||||||||||
| Cell line databases/resources | CLO; CLO_0050934 | ||||||||||||||||||
| Anatomy/cell type resources | BTO; BTO_0003588 | ||||||||||||||||||
| Encyclopedic resources | Wikidata; Q54882719 | ||||||||||||||||||
| Entry history | |||||||||||||||||||
| Entry creation | 22-Oct-2012 | ||||||||||||||||||
| Last entry update | 10-Apr-2025 | ||||||||||||||||||
| Version number | 23 | ||||||||||||||||||