Cellosaurus H9 AAVS1-TRE3G-NGN2 RETREG3-/- RETREG2-/- (CVCL_D1IB)
| Cell line name | H9 AAVS1-TRE3G-NGN2 RETREG3-/- RETREG2-/- | |||
|---|---|---|---|---|
| Synonyms | H9 ES AAVS1-NGN2 FAM134C/A-/- | |||
| Accession | CVCL_D1IB | |||
| Resource Identification Initiative | To cite this cell line use: H9 AAVS1-TRE3G-NGN2 RETREG3-/- RETREG2-/- (RRID:CVCL_D1IB) | |||
| Comments | Characteristics: Using CRISPR/Cas9 a TRE3G promoter driven NEUROG2 construct was introduced in the AAVS1 safe harbor locus (from parent cell line). Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:28450; RETREG2. Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:27258; RETREG3. Genetic integration: Method=CRISPR/Cas9; Gene=HGNC; HGNC:13805; NEUROG2. Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358. Cell type: Embryonic stem cell; CL=CL_0002322. | |||
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | |||
| Hierarchy | Parent: CVCL_D1IA (H9 AAVS1-TRE3G-NGN2 RETREG3-/-) Children:
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| Sex of cell | Female | |||
| Age at sampling | Blastocyst stage | |||
| Category | Embryonic stem cell | |||
| Publications | PubMed=38429475; DOI=10.1038/s41556-024-01356-4; PMCID=PMC10940164 | |||
| Cross-references | ||||
| Encyclopedic resources | Wikidata; Q127380997 | |||
| Entry history | ||||
| Entry creation | 30-Jan-2024 | |||
| Last entry update | 19-Dec-2024 | |||
| Version number | 3 | |||