Cellosaurus logo
expasy logo

Cellosaurus NS-5 (CVCL_D1HI)

[Text version]
Cell line name NS-5
Synonyms NS5
Accession CVCL_D1HI
Resource Identification Initiative To cite this cell line use: NS-5 (RRID:CVCL_D1HI)
Comments Characteristics: Can differentiate into both astrocytes and neurons (PubMed=16086633).
Characteristics: Expresses eGFP under the control of the Sox-1 promoter (from parent cell line).
Selected for resistance to: ChEBI; CHEBI:9555; Tioguanine (6-thioguanine; 6-TG).
Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Neural stem cell; CL=CL_0000047.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: 129P2/Ola.
Hierarchy Parent: CVCL_Y482 (46C)
Sex of cell Male
Age at sampling Blastocyst stage
Category Somatic stem cell

PubMed=16086633; DOI=10.1371/journal.pbio.0030283
Conti L., Pollard S.M., Gorba T., Reitano E., Toselli M., Biella G., Sun Y.-R., Sanzone S., Ying Q.-L., Cattaneo E., Smith A.G.
Niche-independent symmetrical self-renewal of a mammalian tissue stem cell.
PLoS Biol. 3:e283.1594-e283.1606(2005)

PubMed=20626555; DOI=10.1111/j.1471-4159.2010.06886.x
Hicks S.D., Middleton F.A., Miller M.W.
Ethanol-induced methylation of cell cycle genes in neural stem cells.
J. Neurochem. 114:1767-1780(2010)

PubMed=30748015; DOI=10.1111/acer.13976
Miller M.W.
p53-mediated activities in NS-5 neural stem cells: effects of ethanol.
Alcohol. Clin. Exp. Res. 43:655-667(2019)

Anatomy/cell type resources BTO; BTO:0006551
Entry history
Entry creation30-Jan-2024
Last entry update30-Jan-2024
Version number1