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Cellosaurus H9-WISP3KO (CVCL_D1GU)

[Text version]
Cell line name H9-WISP3KO
Accession CVCL_D1GU
Resource Identification Initiative To cite this cell line use: H9-WISP3KO (RRID:CVCL_D1GU)
Comments Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:12771; CCN6.
Omics: Transcriptome analysis by RNAseq.
Omics: Transcriptome analysis by single cell RNAseq.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Disease Progressive pseudorheumatoid dysplasia (NCIt: C202612)
Progressive pseudorheumatoid arthropathy of childhood (ORDO: Orphanet_1159)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9773 (WA09)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
Publications

PubMed=37679035; DOI=10.1136/ard-2023-224304
Li C.-C., Alemany-Ribes M., Raftery R.M., Nwoko U., Warman M.L., Craft A.M.
Directed differentiation of human pluripotent stem cells into articular cartilage reveals effects caused by absence of WISP3, the gene responsible for progressive pseudorheumatoid arthropathy of childhood.
Ann. Rheum. Dis. 82:1547-1557(2023)

Cross-references
Encyclopedic resources Wikidata; Q127381017
Gene expression databases GEO; GSM7192008
GEO; GSM7192009
GEO; GSM7192010
GEO; GSM7192028
GEO; GSM7192029
Entry history
Entry creation30-Jan-2024
Last entry update19-Dec-2024
Version number3