Cellosaurus cell line ImGIST (CVCL

Cellosaurus ImGIST (CVCL_D1GJ)

[Text version]

Cell line name

ImGIST

Synonyms

Immortalized GastroIntestinal Stromal Tumor cells

Accession

CVCL_D1GJ

Resource Identification Initiative

To cite this cell line use: ImGIST (RRID:CVCL_D1GJ)

Comments

Population: Chinese.
Doubling time: 37.8 hours (PubMed=37686448).
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Stomach; UBERON=UBERON_0000945.
Cell type: Interstitial cell of Cajal; CL=CL_0002088.

Sequence variations

Mutation; HGNC; HGNC:6342; KIT; Simple; p.Val560del (c.1676TTG[1]); ClinVar=VCV000375913; Zygosity=Unspecified (PubMed=37686448).

Disease

Gastrointestinal stromal tumor (NCIt: C3868)
Gastrointestinal stromal tumor (ORDO: Orphanet_44890)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Female

Age at sampling

64Y

Category

Transformed cell line

STR profile

Source(s): PubMed=37686448

Markers:

Amelogenin	X
CSF1PO	10,11
D1S1656	11,16
D2S1338	22,24
D3S1358	15,17
D5S818	10,12
D6S1043	12
D7S820	8,13
D8S1179	10,11
D12S391	19,20
D13S317	8
D16S539	11,12
D18S51	17
D19S433	16,17.2
D21S11	29,30
FGA	23,24
Penta D	10,11
Penta E	12,20
TH01	9,10
TPOX	8
vWA	14

Publications

PubMed=37686448; DOI=10.3390/ijms241713640; PMCID=PMC10487453
Hu X.-C., Su P., Liu B., Guo J.-W., Wang Z.-T., He C., Wang Z., Kou Y.-W.
Characterization of a human gastrointestinal stromal tumor cell line established by SV40LT-mediated immortalization.
Int. J. Mol. Sci. 24:13640.1-13640.15(2023)

Cross-references

Encyclopedic resources

Wikidata; Q127382353

Entry history

Entry creation

30-Jan-2024

Last entry update

19-Dec-2024

Version number