ID   ImGIST
AC   CVCL_D1GJ
SY   Immortalized GastroIntestinal Stromal Tumor cells
DR   Wikidata; Q127382353
RX   PubMed=37686448;
CC   Population: Chinese.
CC   Doubling time: 37.8 hours (PubMed=37686448).
CC   Sequence variation: Mutation; HGNC; HGNC:6342; KIT; Simple; p.Val560del (c.1676TTG[1]); ClinVar=VCV000375913; Zygosity=Unspecified (PubMed=37686448).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Stomach; UBERON=UBERON_0000945.
CC   Cell type: Interstitial cell of Cajal; CL=CL_0002088.
ST   Source(s): PubMed=37686448
ST   Amelogenin: X
ST   CSF1PO: 10,11
ST   D12S391: 19,20
ST   D13S317: 8
ST   D16S539: 11,12
ST   D18S51: 17
ST   D19S433: 16,17.2
ST   D1S1656: 11,16
ST   D21S11: 29,30
ST   D2S1338: 22,24
ST   D3S1358: 15,17
ST   D5S818: 10,12
ST   D6S1043: 12
ST   D7S820: 8,13
ST   D8S1179: 10,11
ST   FGA: 23,24
ST   Penta D: 10,11
ST   Penta E: 12,20
ST   TH01: 9,10
ST   TPOX: 8
ST   vWA: 14
DI   NCIt; C3868; Gastrointestinal stromal tumor
DI   ORDO; Orphanet_44890; Gastrointestinal stromal tumor
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   64Y
CA   Transformed cell line
DT   Created: 30-01-24; Last updated: 19-12-24; Version: 3
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RX   PubMed=37686448; DOI=10.3390/ijms241713640; PMCID=PMC10487453;
RA   Hu X.-C., Su P., Liu B., Guo J.-W., Wang Z.-T., He C., Wang Z.,
RA   Kou Y.-W.;
RT   "Characterization of a human gastrointestinal stromal tumor cell line
RT   established by SV40LT-mediated immortalization.";
RL   Int. J. Mol. Sci. 24:13640.1-13640.15(2023).
//