Cellosaurus hIPSC-Tri21-C2-4 (CVCL_D1F9)
| Cell line name | hIPSC-Tri21-C2-4 | ||
|---|---|---|---|
| Synonyms | Tri C2-4; C2-4 | ||
| Accession | CVCL_D1F9 | ||
| Resource Identification Initiative | To cite this cell line use: hIPSC-Tri21-C2-4 (RRID:CVCL_D1F9) | ||
| Comments | Population: Caucasian. Characteristics: Using CRISPR/Cas9 a IRES-TK-Neo-polyA site cassette was introduced in one allele of exon 3 of APP on chromosome 21 (PubMed=23084023). Genetic integration: Method=CRISPR/Cas9; Gene=UniProtKB; Q9QNF7; Human herpesvirus 1 TK. Genetic integration: Method=CRISPR/Cas9; Gene=UniProtKB; P00552; Transposon Tn5 neo. Derived from site: In situ; Chest, skin; UBERON=UBERON_0001868. Cell type: Fibroblast of skin; CL=CL_0002620. | ||
| Disease | Down syndrome (NCIt: C2993) Down syndrome (ORDO: Orphanet_870) | ||
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||
| Hierarchy | Parent: CVCL_X867 (AG06872) Children:
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| Sex of cell | Female | ||
| Age at sampling | 1Y | ||
| Category | Induced pluripotent stem cell | ||
| Publications | PubMed=23084023; DOI=10.1016/j.stem.2012.08.004; PMCID=PMC3705773 | ||
| Cross-references | |||
| Cell line collections (Providers) | WiCell; hipsc-tri21-c2-4 | ||
| Encyclopedic resources | Wikidata; Q127381765 | ||
| Entry history | |||
| Entry creation | 30-Jan-2024 | ||
| Last entry update | 10-Sep-2024 | ||
| Version number | 2 | ||