• Mutation; HGNC; 583; APC; Simple; p.Glu1309Ter (c.3925G>T); ClinVar=VCV000824390; Zygosity=Unspecified (PubMed=24755471).
  
• Mutation; HGNC; 6407; KRAS; Simple; p.Gln61Arg (c.182A>G); ClinVar=VCV000045115; Zygosity=Unspecified (PubMed=20570890; PubMed=24755471).
  
• Mutation; HGNC; 6770; SMAD4; Simple; p.Cys363Tyr (c.1088G>A); ClinVar=VCV000233663; Zygosity=Unspecified (PubMed=24755471).
  

CLPUB00125
Tibbetts L.M., Chu M.Y., Spremulli E.N., Leduc E.H., Calabresi P.
Loss and restoration of tumorigenicity in a human mesothelioma cell line.
Proc. Am. Assoc. Cancer Res. 25:45-45(1984)

PubMed=2837323
Tibbetts L.M., Chu M.Y., Vezeridis M.P., Miller P.G., Tibbetts L.L., Poisson M.H., Camara P.D., Calabresi P.
Cell culture of the mucinous variant of human colorectal carcinoma.
Cancer Res. 48:3751-3759(1988)

PubMed=8422623; DOI=10.1002/1097-0142(19930115)71:2<315::AID-CNCR2820710208>3.0.CO;2-B
Tibbetts L.M., Doremus C.M., Tzanakakis G.N., Vezeridis M.P.
Liver metastases with 10 human colon carcinoma cell lines in nude mice and association with carcinoembryonic antigen production.
Cancer 71:315-321(1993)

PubMed=20570890; DOI=10.1158/0008-5472.CAN-10-0192
Janakiraman M., Vakiani E., Zeng Z.-S., Pratilas C.A., Taylor B.S., Chitale D., Halilovic E., Wilson M., Huberman K., Ricarte Filho J.C.M., Persaud Y., Levine D.A., Fagin J.A., Jhanwar S.C., Mariadason J.M., Lash A., Ladanyi M., Saltz L.B., Heguy A., Paty P.B., Solit D.B.
Genomic and biological characterization of exon 4 KRAS mutations in human cancer.
Cancer Res. 70:5901-5911(2010)

PubMed=24755471; DOI=10.1158/0008-5472.CAN-14-0013
Mouradov D., Sloggett C., Jorissen R.N., Love C.G., Li S., Burgess A.W., Arango D., Strausberg R.L., Buchanan D., Wormald S., O'Connor L., Wilding J.L., Bicknell D.C., Tomlinson I.P.M., Bodmer W.F., Mariadason J.M., Sieber O.M.
Colorectal cancer cell lines are representative models of the main molecular subtypes of primary cancer.
Cancer Res. 74:3238-3247(2014)

PubMed=25944804; DOI=10.1158/1078-0432.CCR-14-2457
Bazzocco S., Dopeso H., Carton-Garcia F., Macaya I., Andretta E., Chionh F., Rodrigues P., Garrido M., Alazzouzi H., Nieto R., Sanchez A., Schwartz S. Jr., Bilic J., Mariadason J.M., Arango D.
Highly expressed genes in rapidly proliferating tumor cells as new targets for colorectal cancer treatment.
Clin. Cancer Res. 21:3695-3704(2015)