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Cellosaurus DS1-iPS4 (CVCL_D012)

[Text version]
Cell line name DS1-iPS4
Synonyms DS1-IPS4
Accession CVCL_D012
Resource Identification Initiative To cite this cell line use: DS1-iPS4 (RRID:CVCL_D012)
Comments From: Children's Hospital Boston; Boston; USA.
Population: Caucasian.
Derived from site: In situ; Chest, skin; UBERON=UBERON_0001868.
Cell type: Fibroblast of skin; CL=CL_0002620.
Disease Down syndrome (NCIt: C2993)
Down syndrome (ORDO: Orphanet_870)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_L780 (AG05397)
Children:
CVCL_C1XZ (DS1-iPS4-Disomic)CVCL_C1Y0 (DS1-iPS4-Trisomic)
Sex of cell Male
Age at sampling 1Y
Category Induced pluripotent stem cell
Publications

PubMed=18691744; DOI=10.1016/j.cell.2008.07.041; PMCID=PMC2633781
Park I.-H., Arora N., Huo H.-G., Maherali N., Ahfeldt T., Shimamura A., Lensch M.W., Cowan C.A., Hochedlinger K., Daley G.Q.
Disease-specific induced pluripotent stem cells.
Cell 134:877-886(2008)

Patent=US20110151447
Park I.-H., Daley G.Q., Agarwal S., Lerou P.H.
Method to produce induced pluripotent stem (iPS) cells from non-embryonic human cells.
Patent number US20110151447, 23-Jun-2011

PubMed=22344463; DOI=10.1126/scitranslmed.3003771; PMCID=PMC4129935
Shi Y.-C., Kirwan P., Smith J., MacLean G.A., Orkin S.H., Livesey F.J.
A human stem cell model of early Alzheimer's disease pathology in Down syndrome.
Sci. Transl. Med. 4:124ra29.1-124ra29.9(2012)

PubMed=23045682; DOI=10.1073/pnas.1215468109; PMCID=PMC3491455
MacLean G.A., Menne T.F., Guo G.-J., Sanchez D.J., Park I.-H., Daley G.Q., Orkin S.H.
Altered hematopoiesis in trisomy 21 as revealed through in vitro differentiation of isogenic human pluripotent cells.
Proc. Natl. Acad. Sci. U.S.A. 109:17567-17572(2012)

Cross-references
Encyclopedic resources Wikidata; Q54831438
Entry history
Entry creation22-Oct-2012
Last entry update10-Sep-2024
Version number16