Cellosaurus cell line CLF_PEDS0005_T1 (CVCL

Cellosaurus CLF_PEDS0005_T1 (CVCL_C9B3)

Cross-references
Cell line name	CLF_PEDS0005_T1
Accession	CVCL_C9B3
Resource Identification Initiative	To cite this cell line use: CLF_PEDS0005_T1 (RRID:CVCL_C9B3)
Comments	Population: African American. Omics: Genomics; Whole exome sequencing. Omics: Transcriptomics; Microarray. Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Sequence variations	Gene deletion; HGNC; HGNC:11103; SMARCB1; Zygosity=Heterozygous (PubMed=30860482). Gene fusion; HGNC; HGNC:28667; C1orf116 + HGNC; HGNC:11103; SMARCB1; Name(s)=SMARCB1-C1orf116; Note=SMARCB1 intron 1 fused to C1orf116 C-terminal (PubMed=30860482).
Disease	Kidney medullary carcinoma (NCIt: C7572) Renal medullary carcinoma (ORDO: Orphanet_319319)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_C9B2 ! CLF_PEDS0005_N CVCL_C9B4 ! CLF_PEDS0005_T2A CVCL_C9B5 ! CLF_PEDS0005_T2B
Category	Cancer cell line
Publications	PubMed=30860482; DOI=10.7554/eLife.44161; PMCID=PMC6436895 Andrew L. Hong, Yuen-Yi Tseng, Jeremiah Anthony Wala, Won-Jun Kim, Bryan D. Kynnap, Mihir B. Doshi, Guillaume Kugener, Gabriel J. Sandoval, Thomas P. Howard, Ji Li, Xiao-Ping Yang ...Show all 41 authors... , Michelle Tillgren, Mahmoud Ghandi, Abeer Sayeed, Rebecca Deasy, Abigail Ward, Brian McSteen, Katherine M. Labella, Paula Keskula, Adam Tracy, Cora Connor, Catherine M. Clinton, Alanna J. Church, Brian D. Crompton, Katherine A. Janeway, Barbara Van Hare, David Sandak, Ole V. Gjoerup, Pratiti Bandopadhayay, Paul A. Clemons, Stuart Lee Schreiber, David E. Root, Prafulla C. Gokhale, Susan N. Chi, Elizabeth A. Mullen, Charles W.M. Roberts, Cigall Kadoch, Rameen Beroukhim, Keith Lloyd Ligon, Jesse S. Boehm, William Chun Hahn; Show fewer authors Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition. eLife 8:e44161.1-e44161.32(2019)
Encyclopedic resources	Wikidata; Q123030936
Gene expression databases	GEO; GSM3039703
Sequence databases	dbGAP; phs001800.v1.p1
Entry history
Entry creation	05-Oct-2023
Last entry update	10-Apr-2025
Version number	4