Cellosaurus GXRCas9 (CVCL_C8ZC)
Cell line name | GXRCas9 |
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Accession | CVCL_C8ZC |
Resource Identification Initiative | To cite this cell line use: GXRCas9 (RRID:CVCL_C8ZC) |
Comments | Population: Caucasian. Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:1606; CCR5. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9. Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P33967; B.cereus Bsr. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Omics: CRISPR phenotypic screen. Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178. Cell type: T-cell; CL=CL_0000084. |
Sequence variations |
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Disease | Childhood T acute lymphoblastic leukemia (NCIt: C7953) Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861) |
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
Hierarchy | Parent: CVCL_C8ZB (CEM-GXR25) |
Sex of cell | Female |
Age at sampling | 3Y11M |
Category | Cancer cell line |
Publications | PubMed=27992415; DOI=10.1038/ng.3741; PMCID=PMC5511375 |
Cross-references | |
CRISP screens repositories | BioGRID_ORCS_Cell_line; 1226 |
Encyclopedic resources | Wikidata; Q123031381 |
Entry history | |
Entry creation | 05-Oct-2023 |
Last entry update | 19-Dec-2024 |
Version number | 4 |