Cellosaurus cell line Caco-2-Luc (CVCL

Cross-references
Cell line name	Caco-2-Luc
Accession	CVCL_C8Y3
Resource Identification Initiative	To cite this cell line use: Caco-2-Luc (RRID:CVCL_C8Y3)
Comments	Population: Caucasian. Genetic integration: Method=Transfection; Gene=UniProtKB; P08659; Firefly luciferase. Genetic integration: Method=Transfection; Gene=UniProtKB; P13249; S.alboniger pac (PuroR). Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations	Mutation; HGNC; 583; APC; Simple; p.Gln1367Ter (c.4099C>T); ClinVar=VCV000376060; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; 2514; CTNNB1; Simple; p.Gly245Ala (c.734G>C); Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; 6770; SMAD4; Simple; p.Asp351His (c.1051G>C); ClinVar=VCV000375998; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; 11998; TP53; Simple; p.Glu204Ter (c.610G>T); ClinVar=VCV000977783; Zygosity=Homozygous (from parent cell line).
Disease	Colon adenocarcinoma (NCIt: C4349)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0025 (Caco-2)
Sex of cell	Male
Age at sampling	72Y
Category	Cancer cell line
Cell line collections (Providers)	Ubigene; YC-D003-Luc-P
Encyclopedic resources	Wikidata; Q123030846
Entry history
Entry creation	05-Oct-2023
Last entry update	10-Sep-2024
Version number	3