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Cellosaurus SW480 M13OE (CVCL_C8D6)

[Text version]
Cell line name SW480 M13OE
Synonyms SW480 MUC13 OverExpressing
Accession CVCL_C8D6
Resource Identification Initiative To cite this cell line use: SW480 M13OE (RRID:CVCL_C8D6)
Comments Population: Caucasian.
Characteristics: Transfected with GFP-tagged MUC13 (PubMed=24097071).
Doubling time: 29.4 hours (PubMed=24097071).
Genetic integration: Method=Transfection/transduction; Gene=HGNC; 7511; MUC13.
Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations
  • Mutation; HGNC; 583; APC; Simple; p.Gln1338Ter (c.4012C>T); ClinVar=VCV000000801; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Pro309Ser (c.925C>T); ClinVar=VCV000458575; Zygosity=Heterozygous (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0546 (SW480)
Sex of cell Male
Age at sampling 51Y
Category Cancer cell line
Publications

PubMed=24097071; DOI=10.1007/s00535-013-0885-z; PMCID=PMC3979492
Gupta B.K., Maher D.M., Ebeling M.C., Stephenson P.D., Puumala S.E., Koch M.R., Aburatani H., Jaggi M., Chauhan S.C.
Functions and regulation of MUC13 mucin in colon cancer cells.
J. Gastroenterol. 49:1378-1391(2014)

Cross-references
Encyclopedic resources Wikidata; Q123033580
Entry history
Entry creation29-Jun-2023
Last entry update10-Sep-2024
Version number3